During immunosuppression, the normal function of the immune system is inhibited. Treatments, such as chemotherapy, disrupt the normal function of the cell cycle, which consequently causes...
Although often associated with extreme conditions and environments such as during military combat, natural disaster or arctic exploration, hypothermia and cold injuries can also occur in more familiar...
Many religions have a strong belief in the sanctity of life, which means that there may be concerns around treatments and care that can be perceived as hastening death, ranging from opioid pain relief...
The United Nations Convention on the Rights of the Child (UNCRC) 1990 defines a child as anyone under 18 years of age. Until a child reaches 18 years of age, an adult (usually their parent—see the...
‘An active and total approach to care, from the point of diagnosis or recognition throughout the child's life, death and beyond. It embraces physical, emotional, social and spiritual elements and...
There are mixed reports on whether randomised controlled trials for children and young people are more or less likely to end prematurely (Schandelmaier et al, 2017; Dufetelle et al, 2018), which is...
Considering co-production, PPI and service user involvement in research, it can be unclear how children and young people have been involved and the impact they have had. In a review of the literature...
Owing to increased medical knowledge and capabilities, more children and young people are living with chronic conditions or long-term complications of treatment. And many are dependent on technology...
It is widely recognised that due to developmental and physiological differences (Joseph et al, 2015; Naka et al, 2017) children and young people's participation in clinical trials is integral to the...
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